Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGOBSERVATIONAL

Biological Bank for Atrial Fibrillation and Stroke

Biological Bank for Studies Related to Atrial Fibrillation and Stroke

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice. This arrhythmia is responsible for 15% of strokes and more than 30% of strokes on people over 65 years. According to studies, 30 to 40% of isolated atrial fibrillations could be familial. Atrial fibrillation has significant genetic heterogeneity. About 40 genes have been identified as potentially involved. Studies have identified genes common to the risk of atrial fibrillation and stroke. Despite the pathophysiology of atrial fibrillation has been intensively and extensively studied for almost a century, there are still many questions. The pathophysiology is not sufficiently understood to allow finding more effective therapies. It is necessary to identify genetic determinants and thus potentially new pharmacological targets more adapted. The establishment of a biological database will test hypotheses concerning the genetic origin and thromboembolic process of atrial fibrillation and associated stroke.

Who May Be Eligible (Plain English)

Group 1a - Inclusion Criteria : \- AF history - Exclusion Criteria : - No AF history - patient who didn't signed consent Group 1b - Inclusion Criteria : - AF history - Scheduled electrophysiological exploration or AF ablation - Exclusion Criteria : - No AF history - pregnant women - patient who didn't signed consent Group 1c - Inclusion Criteria : - AF/AT history - Stroke history - Exclusion Criteria : - No Stroke history - patient who didn't signed consent Group 2 - Inclusion Criteria : - patient over 80 - ECG: sinusal rhythm - TTE : no left atrial dilatation - Exclusion Criteria : - atrial fibrillation history - TTE : Left atria \>25cm², \> 34m/m2), FEVG \< 50% - ECG : QRS \> 90 ms - cardiac pathologies (excepted hypertension and valvulopathies) - History of stroke and transient ischemic attack - patient who didn't signed consent Group 3 - Inclusion Criteria : - cryptogenic stroke or transient ischemic attack history before 50 yo - No AF history - Exclusion Criteria : - AF history - stroke or transient ischemic attack over 50 yo - patient who didn't signed consent Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Group 1a * Inclusion Criteria : \- AF history * Exclusion Criteria : * No AF history * patient who didn't signed consent Group 1b * Inclusion Criteria : * AF history * Scheduled electrophysiological exploration or AF ablation * Exclusion Criteria : * No AF history * pregnant women * patient who didn't signed consent Group 1c * Inclusion Criteria : * AF/AT history * Stroke history * Exclusion Criteria : * No Stroke history * patient who didn't signed consent Group 2 * Inclusion Criteria : * patient over 80 * ECG: sinusal rhythm * TTE : no left atrial dilatation * Exclusion Criteria : * atrial fibrillation history * TTE : Left atria \>25cm², \> 34m/m2), FEVG \< 50% * ECG : QRS \> 90 ms * cardiac pathologies (excepted hypertension and valvulopathies) * History of stroke and transient ischemic attack * patient who didn't signed consent Group 3 * Inclusion Criteria : * cryptogenic stroke or transient ischemic attack history before 50 yo * No AF history * Exclusion Criteria : * AF history * stroke or transient ischemic attack over 50 yo * patient who didn't signed consent

Treatments Being Tested

BIOLOGICAL

Blood taken

Collection of clinical data

GENETIC

Blood taken

Collection of DNA

GENETIC

Blood taken

Collection of plasma

Locations (5)

Service neurologie Centre hospitalier Fleyriat
Bourg-en-Bresse, France
Service d'urgences Neurovasculaires - service de neurologie vasculaire , Hôpital Pierre Wertheimer
Bron, France
Service de rythmologie, hôpital cardiologique Louis Pradel
Bron, France
Service de médecine gériatrique Centre hospitalier Lyon Sud, Groupement hospitalier Sud
Pierre-Bénite, France
Hôpital des charpennes
Villeurbanne, France