Personalized Theratyping Trial

Who May Qualify: - Diagnosis of CF - Age ≥6 y.o. - CFTR mutation that may respond to approved correctors/potentiators in the opinion of the study investigators - willing to sign a consent form/Assent - Stable CF pulmonary regimen Who Should NOT Join This Trial: - Exacerbation requiring antibiotic or steroids for \>28 days before trial entry - Ongoing participation in a CFTR modulator study - Active smoking in the past 6 months - History of solid organ transplant - Any condition which precludes the use of CFTR modulators: e.g. advanced cirrhosis, End-stage Renal Disease (ESRD) - Any condition that precludes the patient from participation in the opinion of the investigator - Any meds that have significant drug-drug interactions or any other off label use of CFTR modulators Always talk to your doctor about whether this trial is right for you.