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RECRUITINGPhase 4INTERVENTIONAL

Study of Immune Responses to Influenza Vaccination

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Better understanding of the immune responses to influenza vaccination is needed in order to understand situations of poor vaccine response. Adults will receive influenza vaccination and then have peripheral blood drawn at pre-defined intervals in order to study the lymphocyte responses.

Who May Be Eligible (Plain English)

Who May Qualify: - Community-dwelling adults able to provide consent who need influenza vaccination for standard of care Who Should NOT Join This Trial: - febrile illness at time of vaccination - active malignancy - use of immunosuppressing medications - blood donation in the past 60 days - influenza vaccinated during the preceding 6 months - allergic reactions to influenza vaccination Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Community-dwelling adults able to provide consent who need influenza vaccination for standard of care Exclusion Criteria: * febrile illness at time of vaccination * active malignancy * use of immunosuppressing medications * blood donation in the past 60 days * influenza vaccinated during the preceding 6 months * allergic reactions to influenza vaccination

Treatments Being Tested

BIOLOGICAL

Influenza vaccination

Adults will receive one intramuscular dose of seasonal quadrivalent inactivated influenza vaccine, as indicated for standard of care.

Locations (1)

University of Pennsylvania
Philadelphia, Pennsylvania, United States