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RECRUITINGINTERVENTIONAL

Cerebellar Stimulation and Cognitive Control

Cerebellar Transcranial Magnetic Stimulation and Cognitive Control

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The purpose of this study is to examine whether cerebellar stimulation can be used to improve cognitive deficits and mood in patients with schizophrenia, autism, bipolar disorder, Parkinson's disease, and major depression.

Who May Be Eligible (Plain English)

Who May Qualify: - A clinical diagnosis consistent with enrollment Who Should NOT Join This Trial: - History of recurrent seizures or epilepsy - Any other neurological or psychiatric diagnosis outside the diagnosis for which the participant is enrolled. - Active substance use disorder in the past 6 months other than tobacco use disorder. - Inability to consent for study. - Pacemaker - Coronary Stent - Defibrillator - Neurostimulation - Claustrophobia - Uncontrolled high blood pressure - Atrial fibrillation - Significant heart disease - Hemodynamic instability - Kidney disease - Pregnant, trying to become pregnant, or breast feeding Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * A clinical diagnosis consistent with enrollment Exclusion Criteria: * History of recurrent seizures or epilepsy * Any other neurological or psychiatric diagnosis outside the diagnosis for which the participant is enrolled. * Active substance use disorder in the past 6 months other than tobacco use disorder. * Inability to consent for study. * Pacemaker * Coronary Stent * Defibrillator * Neurostimulation * Claustrophobia * Uncontrolled high blood pressure * Atrial fibrillation * Significant heart disease * Hemodynamic instability * Kidney disease * Pregnant, trying to become pregnant, or breast feeding

Treatments Being Tested

DEVICE

Repetitive Transcranial Magnetic Stimulation (rTMS)

Subjects with neuropsychiatric diagnoses and matched-controls will be receive theta frequency stimulation of the cerebellum. We will target the cerebellar vermis.

DEVICE

Sham Repetitive Transcranial Magnetic Stimulation (rTMS)

Subjects with neuropsychiatric diagnoses and matched-controls will be receive sham stimulation of the cerebellum. We will target the cerebellar vermis.

Locations (1)

University of Iowa
Iowa City, Iowa, United States