RECRUITINGOBSERVATIONAL
Longitudinal Observational Study Of Chinese With NAFLD/NASH
Prospective Cohort Assessing The Prevalence And Progress Of Non-Alcoholic Fatty Liver Disease (NAFLD)/Non-Alcoholic Steatohepatitis (NASH) In Chinese Subjects
About This Trial
This is a 10-year, longitudinal, observational study of patients with NAFLD/NASH designed to specifically address important clinical questions that remain incompletely answered from registration trials. In addition to the study database, the biospecimen repository will also be included so that translational studies of genomics and biomarkers of response may be performed.
Who May Be Eligible (Plain English)
Who May Qualify:
- Males or females aged 18 and older;
- Adults being managed or treated for NAFL or NASH;
- Be able to communicate meaningfully with the Investigator and be legally competent to provide written willing to sign a consent form.
Who Should NOT Join This Trial:
- Incompetent to understand and/or sign the willing to sign a consent form;
- Ethanol consumption exceeding more than 14 standard beverages per week for males and more than 7 standard beverages per week for female;
- Causes for secondary hepatic fat accumulation such as significant alcohol consumption, medications, Wilson's disease, viral infections, starvation or parenteral nutrition, among others, and conditions associated with microvesicular steatosis
- Diagnosis of liver cirrhosis and/or hepatocellular carcinoma;
- Diagnosis of chronic inflammatory disease (i.e. inflammatory bowel disease, rheumatoid arthritis, inflammatory lung disease, severe infectious diseases), other than NAFL/NASH.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Males or females aged 18 and older;
* Adults being managed or treated for NAFL or NASH;
* Be able to communicate meaningfully with the Investigator and be legally competent to provide written informed consent.
Exclusion Criteria:
* Incompetent to understand and/or sign the informed consent;
* Ethanol consumption exceeding more than 14 standard beverages per week for males and more than 7 standard beverages per week for female;
* Causes for secondary hepatic fat accumulation such as significant alcohol consumption, medications, Wilson's disease, viral infections, starvation or parenteral nutrition, among others, and conditions associated with microvesicular steatosis
* Diagnosis of liver cirrhosis and/or hepatocellular carcinoma;
* Diagnosis of chronic inflammatory disease (i.e. inflammatory bowel disease, rheumatoid arthritis, inflammatory lung disease, severe infectious diseases), other than NAFL/NASH.
Locations (1)
Humanity and Health Medical Centre
Hong Kong, Hong Kong