Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGINTERVENTIONAL

A Randomized Trial to Assess the Role of Imaging During Follow Up After Radical Surgery of High Risk Melanoma

A Prospective Randomized Multicenter Trial to Assess the Role of Imaging During Follow Up After Radical Surgery of Stage IIb-c and III Cutaneous Malignant Melanoma

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

It is not known whether radiological assessments during follow up after surgery for high risk melanoma improve survival. Since radiological examinations are resource demanding, could inflict worry and cause irradiation exposure it is an important question to address. With the introduction of effective medical treatments for malignant melanoma patients, there is a tendency to introduce radiological assessments despite the lack of evidence.

Who May Be Eligible (Plain English)

Who May Qualify: - At least 18 years of age. - Radical surgery for Cutaneous Malignant Melanoma (CMM) stage IIb-c and III. - Sufficient renal function for i.v. contrast scannings. Who Should NOT Join This Trial: - The patient is assessed as unfit to receive treatment in the case of recurrence. - Life-expectancy less than 2 years due to concurrent disease (e.g., cardiac disease, terminal multiple sclerosis, liver cirrhosis). - Inability to provide willing to sign a consent form or refusal to do so. - Inability to comply with the control or intense follow-up program. - Participation in other clinical trials interfering with the control-program. - Existing or previous malignancies within the past 5 years (except for in situ breast and cervical cancer, melanoma in situ and non-melanoma skin cancer). - Pregnancy or currently planned pregnancy. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * At least 18 years of age. * Radical surgery for Cutaneous Malignant Melanoma (CMM) stage IIb-c and III. * Sufficient renal function for i.v. contrast scannings. Exclusion Criteria: * The patient is assessed as unfit to receive treatment in the case of recurrence. * Life-expectancy less than 2 years due to concurrent disease (e.g., cardiac disease, terminal multiple sclerosis, liver cirrhosis). * Inability to provide informed consent or refusal to do so. * Inability to comply with the control or intense follow-up program. * Participation in other clinical trials interfering with the control-program. * Existing or previous malignancies within the past 5 years (except for in situ breast and cervical cancer, melanoma in situ and non-melanoma skin cancer). * Pregnancy or currently planned pregnancy.

Treatments Being Tested

PROCEDURE

CT or PET scans

Scans and blood tests are scheduled at baseline, months 6, 12, 24 and 36.

Locations (20)

Södra Älvsborgs sjukhus
Borås, Sweden
Mälarsjukhuset Eskilstuna
Eskilstuna, Sweden
Falu lasarett
Falun, Sweden
Gävle sjukhus
Gävle, Sweden
Department of Surgery, Sahlgrenska University Hospital
Gothenburg, Sweden
Helsingborgs lasarett
Helsingborg, Sweden
Länssjukhuset Ryhov
Jönköping, Sweden
Länssjukhuset i Kalmar
Kalmar, Sweden
Centralsjukhuset i Karlstad
Karlstad, Sweden
Linköping University Hospital
Linköping, Sweden
Skåne University Hospital
Malmo, Sweden
Örebro University Hospital
Örebro, Sweden
Skaraborgs sjukhus Skövde
Skövde, Sweden
Karolinska University Hospital
Stockholm, Sweden
Länssjukhuset Sundsvall
Sundsvall, Sweden
Uddevalla sjukhus
Uddevalla, Sweden
Umeå University Hospital
Umeå, Sweden
Akademiska sjukhuset
Uppsala, Sweden
Västmanlands sjukhus Västerås
Västerås, Sweden
Visby lasarett
Visby, Sweden