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RECRUITINGOBSERVATIONAL

The K-Map Study, Global Prevalence of KC

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Keratoconus is a ocular disease classified under ectatic diseases which often results in bilateral and asymmetrical corneal distortion. It usually affects patients at young age and can cause severe visual loss. The overall goal of this study is to assess the prevalence of keratoconus (KC) in children and adolescents in various regions of the world based on modern tomographic imaging methods, and to verify whether the occurrence rates reported from literature should be corrected. Our hypothesis is that the prevalence of the disease is much higher than that traditionally reported. At each site, corneal tomography examinations (Pentacam) will be performed bilaterally in children and adolescents, who are not ill or with any ophthalmological symptom. The population to be studied will be composed of children and adolescents on medical visits for non-ophthalmologic reasons, aged between 6 and 20 years. Multiple cities, from different continents (North America, South America, Asia and Europe) will participate.

Who May Be Eligible (Plain English)

Who May Qualify: - Male or female, 6-23 years of age. - Subjects seen for a non-ophthalmic appointment - Provide signed and dated patient consent form (signed by parents / legal guardians). - Willing to comply with all study procedures and be available for the duration of the study Who Should NOT Join This Trial: - Patients with a preexisting ocular disease / condition - Pregnancy or breastfeeding Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Male or female, 6-23 years of age. * Subjects seen for a non-ophthalmic appointment * Provide signed and dated patient consent form (signed by parents / legal guardians). * Willing to comply with all study procedures and be available for the duration of the study Exclusion Criteria: * Patients with a preexisting ocular disease / condition * Pregnancy or breastfeeding

Treatments Being Tested

DIAGNOSTIC_TEST

Rotating Scheimpflug camera (Pentacam HR)

One visit to Ophthalmology Department is required from participant. Parents or legal guardians must attend with their child. The interview and test during visit take approximately 15 minutes. Interview includes filling out a questionnaire about risk factors of the disease and double check on understanding the consent form. The child will sit in front of the instrument (Pentacam HR Scheimpflug imaging system). The rotational measuring procedure generates Scheimpflug images in three dimensions. The images taken during the examination are digitalized, and all image data are transferred to the computer. It calculates a 3D virtual model of the anterior eye segment, from which all additional information is derived.

Locations (12)

USC Roski Eye Institute
Los Angeles, California, United States
Eye Hospital of Wenzhou Medical College
Wenzhou, China
Facility name not listed
Zagreb, Croatia
Facility name not listed
Alexandria, Egypt
Facility name not listed
Homburg, Germany
Facility name not listed
Isfahan, Iran
Facility name not listed
Amman, Jordan
Facility name not listed
Monterrey, Mexico
Facility name not listed
Lima, Peru
Ufa Eye Research Intitute
Ufa, Russia
King Saud University
Riyadh, Saudi Arabia
Facility name not listed
Bukhara, Uzbekistan