RECRUITINGOBSERVATIONAL
Registry of Cell Therapy in Non-Ischemic Dilated Cardiomyopathy
About This Trial
Although several studies have demonstrated beneficial effects of stem cell therapy in patients with non-ischemic dilated cardiomyopathy, the long term benefits and predictors of response to therapy remain undefined. The aim of this registry is to pool long-term clinical data in patients with non-ischemic dilated cardiomyopathy undergoing autologous cell therapy in an attempt to better define predictors of response to such treatment.
Who May Be Eligible (Plain English)
Who May Qualify:
- Patient inclusion criteria consisted of the following: age 18-65 years old, diagnosis of DCM according to the European Society of Cardiology position statement (9), optimal medical management for at least 6 months, left ventricular ejection fraction (LVEF) \<40%, and New York Heart Association functional Class III on stable medical therapy for at least 3 months before referral.
Who Should NOT Join This Trial:
- Patients with acute multi-organ failure or a history of hematologic neoplasms were not included.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Patient inclusion criteria consisted of the following: age 18-65 years old, diagnosis of DCM according to the European Society of Cardiology position statement (9), optimal medical management for at least 6 months, left ventricular ejection fraction (LVEF) \<40%, and New York Heart Association functional Class III on stable medical therapy for at least 3 months before referral.
Exclusion Criteria:
* Patients with acute multi-organ failure or a history of hematologic neoplasms were not included.
Treatments Being Tested
BIOLOGICAL
Autologous stem cell therapy
All patients received granulocyte-colony stimulating factor (G-CSF; 5 mg/kg, 5 days). CD34+ cell were then collected by apheresis and injected transendocardially or intracororonary.
Locations (1)
UMC Ljubljana
Ljubljana, Slovenia