RECRUITINGOBSERVATIONAL
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study
Celiac Disease Genomic Environmental Microbiome and Metabolomic (CDGEMM) Study
About This Trial
Celiac disease (CD) is a complex disease caused by eating gluten, a protein contained in wheat, rye, and barley. It is well known that many factors contribute to the development of CD, including the genes that you have and the foods that you eat. In the CDGEMM study, we will consider as many of these factors as possible and study how they each contribute to disease development. If the investigators find that any one factor, or combination of factors, increases the risk of developing CD, we will be able to apply this information and help prevent or detect disease in high-risk children in the future.
Who May Be Eligible (Plain English)
Who May Qualify:
- Newborns and infants less than 6 months of age who have not been introduced to solid foods (exclusive breast milk or formula diet)
- First-degree relatives of patients affected with biopsy-proven CD
Who Should NOT Join This Trial:
- Infants older than 6 months of age
- Inability or unwillingness of legal guardian/representative to give written willing to sign a consent form
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Newborns and infants less than 6 months of age who have not been introduced to solid foods (exclusive breast milk or formula diet)
* First-degree relatives of patients affected with biopsy-proven CD
Exclusion Criteria:
* Infants older than 6 months of age
* Inability or unwillingness of legal guardian/representative to give written informed consent
Locations (2)
MassGeneral Hospital for Children
Boston, Massachusetts, United States
University of Roma La Sapienza
Rome, Italy