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Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

16 clinical trials · 16 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

RECRUITINGNCT05466786

Distribution of the Homologous Recombination-related (HRR) Genesmutationsand HRD in Breast Cancer

This is a cross-sectional and an observational study, investigator-initiated study in HER2-low breast cancer patients. Approximately 255 subjects with HRD (homologous...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 2551 location
Breast CancerHER2-low Breast Cancer
RECRUITINGPhase 3NCT06278870

Disitamab Vedotin + Pyrotinib Versus THP in the First-line Treatment for HER2+ Advanced Breast Cancer Clinical Trial

The goal of this multicentre, randomized, double-blind controlled, phase III clinical trial is to compare the efficacy and safety of disitamab vedotin in combination with...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 3121 location
HER2-positive Metastatic Breast CancerFirst-line Treatment
RECRUITINGPhase 2NCT06540729

RC48 in Combination With AK104 and Bevacizumab in OCCC

Disitamab vedotin (RC48) in combination with AK104 (PD-1/CTLA-4 bispecific) and bevacizumab for the treatment of recurrent and persistent clear cell ovarian cancer: a single-arm,...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 391 location
Ovary Cancer
RECRUITINGPhase 1 / Phase 2NCT05924997

Adebrelimab, Camrelizumab Plus Apatinib as First-line Therapy in Patients With Advanced Hepatocellular Carcinoma

This is a prospective, single-arm, phase Ib/II trial . The objective of this study is to evaluate the efficacy and safety of adebrelimab, camrelizumab plus apatinib as first-line...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 521 location
Advanced Hepatocellular Carcinoma
RECRUITINGNCT06909643

Development and Prospective Validation of a Multimodal Fusion Artificial Intelligence Model for Predicting the Efficacy...

This study is a multi-center observational study without interventions, including the construction of an AI diagnostic model and retrospective testing of a multi-center cohort....

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 5501 location
CancerNeoadjuvant Therapy
RECRUITINGNCT07051083

Bladder Cancer Staging and Prediction of New Adjuvant Chemotherapy Efficacy Based on Deep Learning and Transfer...

Bladder cancer is the most common malignant tumor of the urinary system. The presence or absence of muscle invasion in early bladder cancer is an independent prognostic factor....

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 4801 location
Bladder CancerStagingDeep Learning+2
RECRUITINGNCT07357571

Preoperative Prediction of Lymph Node Metastasis in T1N0M0 Papillary Thyroid Carcinoma by Using Contrast-enhanced...

Similarly, the burden of central lymph node metastasis affects the individualized management of patients with T1N0M0 papillary thyroid carcinoma (PTC): lymph node metastasis is a...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 6002 locations
Thyroid Papillary CarcinomaContrast Enhanced Ultrasound
RECRUITINGNCT06623578

Comparative Study of Transaxillary Robotic Thyroidectomy With MRND Versus Conventional Open Surgery in N1b PTC

Thyroid cancer is one of the most common malignant tumors in women, ranking seventh in the United States and fourth in China. Papillary thyroid carcinoma is the most common...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 8761 location
Papillary Thyroid CarcinomaLymphatic Metastasis
RECRUITINGNCT06592755

Single-Incision Gasless Endoscopic Total Thyroidectomy Via Subclavian Approach Versus Open Surgery for PTC

Historically, performing a contralateral thyroid lobectomy and lymph node dissection via the subclavian approach was considered challenging. This study aimed to evaluate the...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 1201 location
Papillary Thyroid Carcinoma
RECRUITINGNCT06146764

CEUS Improves the Diagnostic Performance of SRSS of Thyroid Carcinoma

Contrast-enhanced ultrasound (CEUS) can sensitively show the blood perfusion characteristics of thyroid nodules, which is a useful supplement to gray-scale ultrasound. However,...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 8001 location
Thyroid NoduleThyroid Carcinoma
RECRUITINGPhase 2NCT06339619

Combination Immunotherapy of Adebrelimab With Apatinib and Tegafur for Immune Rechallenge Therapy in Esophageal...

The goal of this single-arm study is to explore the efficacy and safety of Adebrelimab in combination with Apatinib and Tegafur for the treatment of locally advanced or metastatic...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 321 location
Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma
RECRUITINGNCT06541626

Sun Yat-Sen Cohort of CNS Idiopathic Inflammatory Demyelinating Diseases

The goal of this observational study is to learn about pathogenesis and clinical prognosis of CNS IIDD in the Chinese population and to provide evidence-based clues for clinical...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 4501 location
Multiple Sclerosis, MSNeuromyelitis Optica Spectrum DisordersMyelin Oligodendrocyte Glycoprotein Antibody-associated Disease+3
RECRUITINGNCT06575322

Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Pain, Anxiety and...

The goal of this observational study is to learn about the Effects of neoadjuvant therapy with carboplatin, paclitaxel combined with anti-PD-1 drugs on pain, anxiety and...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 3021 location
Head and Neck Squamous Cell Carcinoma
RECRUITINGNCT06301373

Methotrexate Combined With Tofacitinib in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is the leading cause of disability in Chinese women. We established a synovial pathology queue in the early stage and proposed a new synovial...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 1301 location
Rheumatoid Arthritis
RECRUITINGNCT05951517

Mycophenolate Mofetil in Gastrointestinal Henoch-Schonlein Purpura

Henoch Schönlein purpura (HSP) is the most common type of vasculitis in children, with an incidence of \~10/100,000, whereas \>90% of the patients develop symptoms at \<10 years...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 241 location
Henoch-Schönlein PurpuraGastrointestinal InjuryMycophenolate Mofetil
RECRUITINGNCT06437652

An AI Algorithm for Lymphocyte Focus Score of Minor Salivary Gland Biopsy Samples for Diagnosing Sjogren's Syndrome

The aim of this research is to discover an artificial intelligence (AI) algorithm for lymphocyte focus score in whole slide images of labial minor salivary gland (SG) biopsy...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 10001 location
Sjogren's Syndrome