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Regeneron Pharmaceuticals

16 clinical trials · 16 recruiting · INDUSTRY

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Regeneron Pharmaceuticals

RECRUITINGNCT05363319

An Observational Study to Assess the Effectiveness and Safety of a Cemiplimab in Adult Patients With Advanced Non-Small...

This study is focused on patients with non-small cell lung cancer (NSCLC) and have been prescribed a cemiplimab (Libtayo®) based treatment regimen under standard care. The goal...

Sponsor: Regeneron PharmaceuticalsEnrolling: 50020 locations
Non-small Cell Lung Cancer
RECRUITINGPhase 2NCT06787612

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

This study is researching an experimental drug called ubamatamab, also referred to as "study drug". The study is focused on patients who have advanced ovarian cancer. The aim of...

Sponsor: Regeneron PharmaceuticalsEnrolling: 22020 locations
Ovarian CancerFallopian Tube CancerPrimary Peritoneal Cancer
RECRUITINGPhase 3NCT06230224

A Trial to Learn How Effective and Safe Odronextamab is Compared to Standard of Care for Adult Participants With...

This study is researching an experimental drug called odronextamab, referred to as study drug. The study is focused on patients with previously treated aggressive B-cell...

Sponsor: Regeneron PharmaceuticalsEnrolling: 21620 locations
B-Cell Non-Hodgkin Lymphoma (B-NHL)
RECRUITINGPhase 2NCT06140524

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple...

This study is researching an investigational drug called linvoseltamab ("study drug") in participants at moderate risk of developing multiple myeloma (about 3 to 10% average...

Sponsor: Regeneron PharmaceuticalsEnrolling: 11613 locations
Monoclonal Gammopathy of Undetermined Significance (MGUS)Smoldering Multiple Myeloma (SMM)
RECRUITINGPhase 1NCT05137054

A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult...

This study is researching an experimental drug called linvoseltamab in combination with other drugs for the treatment of a blood cancer called multiple myeloma. Linvoseltamab has...

Sponsor: Regeneron PharmaceuticalsEnrolling: 31720 locations
Multiple Myeloma
RECRUITINGPhase 1 / Phase 2NCT06292780

A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain...

This study is researching an experimental drug called linvoseltamab ("study drug"). This study is focused on patients who have AL amyloidosis that has returned or have failed...

Sponsor: Regeneron PharmaceuticalsEnrolling: 22018 locations
Relapsed/Refractory Systemic Light Chain Amyloidosis
RECRUITINGPhase 1 / Phase 2NCT03761108

Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory Multiple Myeloma

The main purpose of this study is to learn about the safety of linvoseltamab and to find out what is the best dose of linvoseltamab to give to patients with multiple myeloma and...

Sponsor: Regeneron PharmaceuticalsEnrolling: 38720 locations
Multiple Myeloma
RECRUITINGPhase 1 / Phase 2NCT06351592

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation...

This study is researching an experimental drug called ALN-SOD (called "study drug"). This study is focused on people with Amyotrophic Lateral Sclerosis (ALS) caused by a change in...

Sponsor: Regeneron PharmaceuticalsEnrolling: 4216 locations
Amyotrophic Lateral Sclerosis (ALS)Mutation in the Superoxide Dismutase-1 (SOD1) Gene
RECRUITINGPhase 1 / Phase 2NCT05788536

A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants With Hearing Loss Due to...

Regeneron is conducting a study of an investigational new drug called DB-OTO. DB-OTO is a gene therapy that is being developed to treat children who have hearing loss due to...

Sponsor: Regeneron PharmaceuticalsEnrolling: 3015 locations
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
RECRUITINGPhase 3NCT07410117

REGN7508 in Adult Participants for Prevention of Cancer-Associated Thrombosis

This study is researching an experimental drug called REGN7508 (called "study drug"). The study is focused on the prevention of Cancer-Associated Thrombosis (CAT) in participants....

Sponsor: Regeneron PharmaceuticalsEnrolling: 8605 locations
Cancer-Associated Thrombosis (CAT)
RECRUITINGPhase 3NCT07213778

REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult...

This study is researching an experimental drug called REGN7508 versus Acetylsalicylic Acid (ASA) (each called "study drug"). The study is focused on adults undergoing elective,...

Sponsor: Regeneron PharmaceuticalsEnrolling: 200010 locations
Symptomatic Venous Thromboembolism (VTE)
RECRUITINGPhase 4NCT06572228

Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to...

This study is researching a drug called dupilumab. The study is focused on patients who have uncontrolled asthma. Asthma is a condition where the airways narrow and swell, making...

Sponsor: Regeneron PharmaceuticalsEnrolling: 25020 locations
Asthma
RECRUITINGPhase 1 / Phase 2NCT06379789

A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265)...

Participants in this study have a genetic mutation, specifically in the coagulation (blood clotting) Factor 9 gene that causes severe or moderately severe hemophilia B. This study...

Sponsor: Regeneron PharmaceuticalsEnrolling: 13020 locations
Hemophilia B
RECRUITINGPhase 1NCT07230834

Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants

This study is researching an experimental drug called pozelimab (called "study drug"). The study is focused on people with a condition where certain parts of the eye's retina stop...

Sponsor: Regeneron PharmaceuticalsEnrolling: 544 locations
Geographic Atrophy (GA)
RECRUITINGPhase 3NCT06541704

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult...

This study is researching experimental (study) drugs called pozelimab and cemdisiran. The study is focused on participants who have Geographic Atrophy (GA) caused by Age-related...

Sponsor: Regeneron PharmaceuticalsEnrolling: 97520 locations
Age-related Macular Degeneration (AMD)Geographic Atrophy (GA)
RECRUITINGPhase 1 / Phase 2NCT07218770

A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants

This study is researching an experimental drug called REGN7041 (also referred to as "study drug"). The study is focused on patients who have active inflammation inside of the eye...

Sponsor: Regeneron PharmaceuticalsEnrolling: 724 locations
Active Noninfectious Uveitis Affecting the Posterior Segment