Nationwide Children's Hospital
3 clinical trials · 3 recruiting · OTHER
Trials by Nationwide Children's Hospital
RECRUITINGPhase 2NCT06838676
ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas
This is a Phase II open-label study to investigate the safety and efficacy of ACT001 in patients with DIPG and H3K27-altered HGG.
Sponsor: Nationwide Children's HospitalEnrolling: 6020 locations
Diffuse Intrinsic Pontine Gliomas (DIPG)Progressive DIPGRefractory DIPG+2
RECRUITINGPhase 2 / Phase 3NCT05267821
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
The TRIPS study is a prospective, multi-center, double-blind, adaptively randomized, placebo-controlled clinical trial of the drug anakinra for reversal of moderate to severe...
Sponsor: Nationwide Children's HospitalEnrolling: 50020 locations
Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
RECRUITINGNCT06264700
Applying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness
This study is for caregivers of young children with sickle cell disease and adolescents with sickle cell disease who are currently prescribed hydroxyurea and are receiving care at...
Sponsor: Nationwide Children's HospitalEnrolling: 603 locations
Sickle Cell Disease