Essen Biotech
3 clinical trials · 3 recruiting · OTHER
Trials by Essen Biotech
RECRUITINGPhase 1 / Phase 2NCT07032129
Sequential CAR-T Cells Targeting BCMA/GPRC5D in Patients With Relapsed/ Refractory Multiple Myeloma
This is an open, single-arm, clinical study to evaluate the efficacy and safety of chimeric antigen receptor T cell immunotherapy (CAR-T) targeting BCMA or GPRC5D or both...
Sponsor: Essen BiotechEnrolling: 601 location
Multiple MyelomaMultiple Myeloma in RelapseMultiple Myeloma Progression+1
RECRUITINGPhase 1 / Phase 2NCT06350110
Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)
This study is a preliminary investigation, with a single-group design, not randomized and transparent, focusing on treatment. Its purpose is to identify the highest dose of BH002...
Sponsor: Essen BiotechEnrolling: 751 location
Systemic Lupus ErythematosusLupus NephritisAutoimmune Diseases+6
RECRUITINGPhase 1 / Phase 2NCT06399107
Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease
This study is an open-label, non-randomized, single-dose Phase 1/2 trial involving around 85 adult and pediatric participants aged between 2 and 50 years with sickle cell disease...
Sponsor: Essen BiotechEnrolling: 851 location
Sickle Cell DiseaseSickle-Cell Disease With Crisis