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TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.

Phase 3 Traumatic Brain Injury Trials

6 Phase 3 trials for Traumatic Brain Injury. Phase 3 trials are the final stage of testing before a treatment can be submitted for FDA approval.

What is a Phase 3 trial?

Phase 3 clinical trials study a treatment in large groups (hundreds to thousands of people) to confirm its effectiveness, monitor side effects, and compare it to standard treatments. These trials are the last major step before the FDA considers approving a new treatment.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
RECRUITINGPhase 3NCT06953674

Saline Versus Balanced Crystalloid in Traumatic Brain Injury

The goal of this clinical trial is to determine which crystalloid (saline or balanced) should be used in the critical management of Traumatic Brain Injury (TBI) in moderate or...

Sponsor: University of LouisvilleEnrolling: 6001 location
RECRUITINGPhase 3NCT04499755

Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics

Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics

Sponsor: Sherief Abd-ElsalamEnrolling: 1001 location
RECRUITINGPhase 3NCT06581003

Hyperbaric Oxygen Treatment for Veterans With Traumatic Brain Injury

The goal of this blinded, adaptive, randomized, placebo-controlled clinical trial is to investigate the use of hyperbaric oxygen as a therapy to treat mild to moderate traumatic...

Sponsor: University of South FloridaEnrolling: 4201 location
RECRUITINGPhase 3NCT04867317

Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone...

The purpose of this study is to determine whether growth hormone replacement therapy (GHRT) is effective versus placebo in the improvement of Quality of Life in patients with...

Sponsor: VA Office of Research and DevelopmentEnrolling: 1724 locations
RECRUITINGPhase 3NCT04521881

Clinical Randomisation of an Anti-fibrinolytic in Symptomatic Mild Head Injury in Older Adults

Tranexamic acid (TXA) reduces head injury deaths. The CRASH-4 trial aims to assess the effects of early intramuscular TXA on intracranial haemorrhage, disability, death, and...

Sponsor: London School of Hygiene and Tropical MedicineEnrolling: 50002 locations
RECRUITINGPhase 3NCT03559114

PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST)

This is a phase III, multi-centre, double blind, randomized controlled trial of patients with traumatic brain injury (TBI).

Sponsor: Sunnybrook Health Sciences CentreEnrolling: 110012 locations