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TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.

Phase 3 Depression Trials

6 Phase 3 trials for Depression. Phase 3 trials are the final stage of testing before a treatment can be submitted for FDA approval.

What is a Phase 3 trial?

Phase 3 clinical trials study a treatment in large groups (hundreds to thousands of people) to confirm its effectiveness, monitor side effects, and compare it to standard treatments. These trials are the last major step before the FDA considers approving a new treatment.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
RECRUITINGPhase 3NCT06966401

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With...

This study will evaluate the long-term safety and tolerability of NBI-1065845 as an adjunctive treatment in participants with MDD.

Sponsor: Neurocrine BiosciencesEnrolling: 60018 locations
RECRUITINGPhase 3NCT06911112

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants...

The study will evaluate the efficacy of NBI-1065845 compared with placebo as an adjunctive treatment in participants with MDD on improving symptoms of depression.

Sponsor: Neurocrine BiosciencesEnrolling: 20010 locations
RECRUITINGPhase 3NCT04041479

Biomarker-guided rTMS for Treatment Resistant Depression

Repetitive transcranial magnetic stimulation (rTMS) is a treatment for depression. The investigators are continuing to learn how to optimize outcomes from rTMS treatment. The...

Sponsor: Weill Medical College of Cornell UniversityEnrolling: 3482 locations
RECRUITINGPhase 3NCT06247839

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder

This open-label functional Magnetic Resonance Imaging (fMRI) study will assess the effects of a single dose of psilocybin on rumination and the neural correlates of rumination in...

Sponsor: Sharmin GhaznaviEnrolling: 201 location
RECRUITINGPhase 3NCT06139926

Clinical Study of Dexmedetomidine Administered Intranasally to Relieve Perioperative Anxiety and Depression in Patients...

Currently, domestic and international research on dexmedetomidine as well as anxiety and depression is more focused on basic research. In terms of clinical research,...

Sponsor: First Affiliated Hospital of Chongqing Medical UniversityEnrolling: 1261 location
RECRUITINGPhase 3NCT04877197

Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients...

The purpose of this study is to demonstrate whether Behavioral Activation for depression delivered via home based telehealth (BA-HT) is effective in improving social and role...

Sponsor: VA Office of Research and DevelopmentEnrolling: 1321 location