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Treatment Resistant Depression Clinical Trials

8 recruiting trials for Treatment Resistant Depression. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
8
Total Trials
8
Recruiting Now
1
Phase 3 Trials
8
Sponsors

Recruiting Trials

RECRUITINGNCT05418894

Mapping and Modulating the Spatiotemporal Dynamics of Socio-Affective Processing

The overall goal of this study is to map the spatiotemporal dynamics of social affective processing and to examine selective modulation of these dynamics in humans undergoing...

Sponsor: Baylor College of MedicineEnrolling: 841 location
RECRUITINGNCT03537794

Characterizing Dopamine Receptor Binding in Treatment Resistant Depression

It is estimated that 30% of individuals with Major Depressive Disorder (MDD) fail to respond to conventional antidepressant medication which accounts for over 1 million Canadians...

Sponsor: Unity Health TorontoEnrolling: 451 location
RECRUITINGPhase 4NCT03272698

ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression

To determine if an high intensity ketamine with ECT rescue (HIKER) approach for treatment resistant depression will: 1) reduce patient suffering by hastening disease remission, 2)...

Sponsor: University of SaskatchewanEnrolling: 621 location
RECRUITINGPhase 3NCT04041479

Biomarker-guided rTMS for Treatment Resistant Depression

Repetitive transcranial magnetic stimulation (rTMS) is a treatment for depression. The investigators are continuing to learn how to optimize outcomes from rTMS treatment. The...

Sponsor: Weill Medical College of Cornell UniversityEnrolling: 3482 locations
RECRUITINGNCT06423430

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

The goal of this clinical trial is to evaluate the effectiveness and safety of bilateral stimulation of the subcallosal cingulate white matter (SCCwm) using Deep Brain Stimulation...

Sponsor: Abbott Medical DevicesEnrolling: 10020 locations
RECRUITINGPhase 2NCT06132178

Psilocybin rTMS for Treatment Resistant Depression

The purpose of this study is to determine the safety and feasibility of sequencing psilocybin therapy with a short-duration, aiTBS protocol (Stanford Accelerated Intelligent...

Sponsor: University of Texas at AustinEnrolling: 1001 location
RECRUITINGNCT03887715

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS...

Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom...

Sponsor: LivaNovaEnrolling: 680020 locations
RECRUITINGNCT04480918

University of Iowa Interventional Psychiatry Service Patient Registry

The purpose of this study is to examine the effects of interventional/procedural therapies for treatment-resistant depression (TRD) and Obsessive-Compulsive Disorder (OCD). These...

Sponsor: Mark NiciuEnrolling: 10001 location