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Phenylketonurias Clinical Trials

8 recruiting trials for Phenylketonurias. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
8
Total Trials
8
Recruiting Now
0
Phase 3 Trials
8
Sponsors

Recruiting Trials

RECRUITINGNCT06560736

Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria

While previous PKU intervention research has largely focused on pharmacological treatment of elevated Phe levels, the adaptation of evidence-based psychosocial therapy holds...

Sponsor: University of Missouri-ColumbiaEnrolling: 301 location
RECRUITINGNCT06337864

Effect of Large Neutral Amino Acids in Adults With Classical Phenylketonuria

The overall aim of this study is to evaluate LNAA treatment as a potential alternative to conventional dietary treatment for PKU. This study investigates the effects of LNAA...

Sponsor: Rigshospitalet, DenmarkEnrolling: 302 locations
RECRUITINGPhase 1 / Phase 2NCT06332807

AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)

This is a Phase 1/2, open-label, multiple-center, dose escalation and cohort expansion study to evaluate the safety and efficacy of NGGT002 in adult subjects with classic...

Sponsor: NGGT INC.Enrolling: 125 locations
RECRUITINGEarly Phase 1NCT06061614

Safety and Efficacy Study of NGGT002 in PKU Adult Subjects

This is a single-center, open-label, non-randomized, dose escalation study to evaluate the safety, tolerability and efficacy of NGGT002 in adult Phenylketonuria (PKU) subjects....

Sponsor: The First Affiliated Hospital of Bengbu Medical UniversityEnrolling: 151 location
RECRUITINGNCT05128149

Metabolic Control and Patient Well-being in Phenylketonuria: do Guidelines Make a Difference?

Treatment of PKU implies for most patients that with strict adherence to dietary treatment they can achieve excellent neurocognitive outcome. Dietary treatment, though, is hard to...

Sponsor: University Children's Hospital, ZurichEnrolling: 2001 location
RECRUITINGNCT06718842

Walking Program in Fatty Liver Children With Phenylketonuria

phenylketonuria (commonly known as PKU) is an inherited disorder that increases the levels of a substance called phenylalanine in the blood. PKU is usually associated with many...

Sponsor: Cairo UniversityEnrolling: 401 location
RECRUITINGNCT04404530

Nutritional Impacts of Palynziq on Patients With Phenylketonuria (PKU)

Phenylketonuria (PKU) is an inherited metabolic disorder that impairs the metabolism of the essential amino acid phenylalanine (Phe). Without stringent dietary control, Phe...

Sponsor: Emory UniversityEnrolling: 452 locations
RECRUITINGPhase 1 / Phase 2NCT06687733

Safety and Efficacy Study of NGGT002 in cPKU Adult Subjects

This is a Phase 1/2, open-label, multiple-center, dose escalation and cohort expansion study to evaluate the safety and efficacy of NGGT002 in adult subjects with classic...

Sponsor: NGGT (Suzhou) Biotechnology Co., Ltd.Enrolling: 182 locations