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Metastatic Melanoma Clinical Trials

11 recruiting trials for Metastatic Melanoma. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
11
Total Trials
11
Recruiting Now
0
Phase 3 Trials
10
Sponsors

Recruiting Trials

RECRUITINGPhase 1NCT04119024

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic...

This phase I trial studies the side effects and best dose of modified immune cells (IL13Ralpha2 CAR T cells) after a chemotherapy conditioning regimen for the treatment of...

Sponsor: Anusha KalbasiEnrolling: 183 locations
RECRUITINGPhase 2NCT03646617

Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma

The main purpose of this study is to determine the safety of combining ipilimumab and nivolumab with hypofractionated radiotherapy to a single tumor in patients with metastatic...

Sponsor: Abramson Cancer Center at Penn MedicineEnrolling: 543 locations
RECRUITINGPhase 2NCT07288203

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Melanoma

This is a Phase 2, multicenter, open-label study of lifileucel (tumor-infiltrating lymphocytes \[TIL\]) in participants with previously treated advanced melanoma

Sponsor: Iovance Biotherapeutics, Inc.Enrolling: 1005 locations
RECRUITINGNCT05878977

Biomarkers in Immunotherapy of Melanoma

Background: Immunotherapy has been successful in treating advanced melanoma, but a large proportion of patients do not respond to the treatment with immune checkpoint inhibitors...

Sponsor: Institute of Oncology LjubljanaEnrolling: 1501 location
RECRUITINGNCT05856565

Generation of an Artificial Intelligence Algorithm Based on the Analysis of Melanoma Peri-scar Dermatoheliosis, as a...

In the last decade, the advent of immunotherapies with inhibitors of immune checkpoints, such as anti-PD-1 and anti-CTLA-4, has revolutionized the treatment of advanced or...

Sponsor: Nantes University HospitalEnrolling: 7004 locations
RECRUITINGNCT03888950

Interim FDG PET-CT in Melanoma Metastatic Patient's Treated by Anti-PD1 Therapy

The objective of this study is to assess whether FDG (18F-2-fluoro-2-deoxy-D-glucose fluorodeoxyglucose) PET-CT could be an early predictive method of therapeutic response to...

Sponsor: Centre Hospitalier Universitaire de NiceEnrolling: 201 location
RECRUITINGPhase 1NCT04903119

Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma

This is a phase 1 dose-escalation study of nilotinib in combination with fixed-dose dabrafenib and trametinib regimen for patients with metastatic or unresectable melanoma...

Sponsor: Rina PlattnerEnrolling: 304 locations
RECRUITINGPhase 1NCT03743298

Safety of AV-MEL-1 With Anti-PD-1 Therapy in Metastatic Melanoma

This is an open label, single-arm, phase IB treatment study to determine the safety of administering anti-PD1 monoclonal antibodies with AV-MEL-1 and to get some suggestion of...

Sponsor: Aivita Biomedical, Inc.Enrolling: 202 locations
RECRUITINGNCT07407166

Efficacy of First-Line Immunotherapy in Metastatic Melanoma in Slovenia and Identification of Predictive Biomarkers

This study evaluates the effectiveness of first-line immunotherapy in patients with metastatic melanoma treated at the Institute of Oncology Ljubljana in Slovenia. The main...

Sponsor: Institute of Oncology LjubljanaEnrolling: 401 location
RECRUITINGPhase 1 / Phase 2NCT06975293

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers

This early phase oncology trial will be conducted at various study centers to investigate the safety, tolerability, and antitumor activity of STC-15 (a METTL3 inhibitor) in...

Sponsor: STORM Therapeutics LTDEnrolling: 1883 locations
RECRUITINGPhase 1NCT04697576

Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma

This phase I trial investigates the effects of influenza vaccine in treating patients with stage I-IV melanoma. While intramuscular administration of influenza vaccine provides...

Sponsor: Carlo ContrerasEnrolling: 361 location