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TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.

Esophageal Squamous Cell Carcinoma Clinical Trials

15 recruiting trials for Esophageal Squamous Cell Carcinoma. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
15
Total Trials
15
Recruiting Now
4
Phase 3 Trials
10
Sponsors

Recruiting Trials

RECRUITINGPhase 1NCT07217171

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced...

The goal of this study is to evaluate the safety and effectiveness of EVOLVE104 in participants with advanced urothelial and squamous cell carcinomas who have previously taken...

Sponsor: EvolveImmune United, IncEnrolling: 1609 locations
RECRUITINGPhase 1 / Phase 2NCT05144698

RAPA-201 Therapy of Solid Tumors

The therapy of solid tumors has been revolutionized by immune therapy, in particular, approaches that activate immune T cells in a polyclonal manner through blockade of checkpoint...

Sponsor: Rapa Therapeutics LLCEnrolling: 371 location
RECRUITINGPhase 1NCT07090499

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

The purpose of the study is to explore the safety and effects of the study drug (PF-08046876) in people diagnosed with advanced cancer of the bladder, lung, head and neck,...

Sponsor: PfizerEnrolling: 31020 locations
RECRUITINGPhase 2NCT07403136

Vebrekotuzumab ± Anti-PD-1 in Pretreated Advanced ESCC

This study will test a new potential treatment for advanced esophageal squamous cell cancer (ESCC) for patients whose initial treatment has stopped working. Currently, the...

Sponsor: Fudan UniversityEnrolling: 521 location
RECRUITINGPhase 2NCT06463834

A Study of Sintilimab Combined With Chemotherapy for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma

This study is aimed to evaluate the efficacy and safety of sintilimab combined with chemotherapy (docetaxel+cisplatin+5-fluorouracil, DCF) in neoadjuvant treatment of locally...

Sponsor: Fujian Cancer HospitalEnrolling: 301 location
RECRUITINGPhase 2NCT06329869

Sacituzumab Govitecan for Advanced Esophageal Squamous Cell Carcinoma

The goal of this clinical trial is to investigate the efficacy and safety of sacituzumab govitecan in patients with advanced esophageal squamous cell carcinoma.

Sponsor: National Taiwan University HospitalEnrolling: 351 location
RECRUITINGPhase 2NCT06006650

Neoadjuvant Therapy for Stage II-IVA Resectable Esophageal Squamous Cell

The aim of this study was to investigate the efficacy and safety of pembrolizumab combined with albumin paclitaxel and cisplatin versus albumin paclitaxel and cisplatin or...

Sponsor: Tang-Du HospitalEnrolling: 1143 locations
RECRUITINGPhase 3NCT04009265

Study Compare Adjuvant Chemotherapy, Chemoradiotherapy and Surgery Alone for pN1-2(pT1b-3N1-2M0) Esophageal Carcinoma

A multi-center prospective randomized controlled study was conducted to compare the effects of adjuvant chemotherapy, chemoradiotherapy and surgery alone for the patients with...

Sponsor: Fujian Medical University Union HospitalEnrolling: 8191 location
RECRUITINGPhase 2NCT06165380

Cardenilimab Combined With Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

The goal of this trial is to test the efficacy and safety of cardenilimab combined with chemotherapy in the conversion therapy of locally advanced unresectable esophageal squamous...

Sponsor: Li ZhangEnrolling: 431 location
RECRUITINGPhase 2NCT07016724

Neoadjuvant Radiochemotherapy Combined With Cadonilizumab for Local Advanced Esophageal Squamous Cell Cancer

Esophageal squamous cell cancer (ESCC) has a high incidence in China. Although the fast development of immune check point inhibitors (ICIs), the rate of pCR is limited with the...

Sponsor: The First Affiliated Hospital of Zhengzhou UniversityEnrolling: 2081 location
RECRUITINGEarly Phase 1NCT06690476

Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of IPM514 in Patients with Esophageal...

This is a open-label, multicenter study to assess the safety, tolerability, and preliminary efficacy of IPM514 in patients with esophageal squamous cell carcinoma. This study...

Sponsor: Peking UniversityEnrolling: 741 location
RECRUITINGPhase 3NCT06194734

A Study of KC1036 Versus Investigator's Choice of Chemotherapy in Patients With Advanced Esophageal Cancer

The purpose of this study is to evaluate the efficacy and safety of KC1036 versus investigator's choice of chemotherapy in patients with advanced recurrent or metastatic...

Sponsor: Beijing Konruns Pharmaceutical Co., Ltd.Enrolling: 4901 location
RECRUITINGPhase 2NCT03964753

Neoadjuvant Therapy With Nab-paclitaxel and Cisplatin for Locally Advanced Esophageal Squamous Cell Carcinoma

To verify the role of nab-paclitaxel in neoadjuvant therapy for esophageal squamous cell carcinoma, the investigators designed a prospective, randomized, controlled , multicente...

Sponsor: Hebei Medical University Fourth HospitalEnrolling: 2021 location
RECRUITINGPhase 3NCT06022861

A Study to Compare the Efficacy and Safety of LY01015 and Opdivo® Combined Respectively With Chemotherapy in Advanced...

This is a randomized, double-blind, multicenter, Phase 3 study to compare the efficacy and safety of LY01015 and Opdivo®(Nivolumab Injection)combined respectively with...

Sponsor: Shandong Boan Biotechnology Co., LtdEnrolling: 5101 location
RECRUITINGPhase 3NCT05919030

A Study of Chemoradiation in Combination with Tislelizumab As First Line Treatment in Participants with Advanced...

This study is a multicentre, randomised, parallel-controlled, open-label, 3 phase clinical trial. The subjects were untreated, unresectable locally advanced, recurrent or...

Sponsor: Renmin Hospital of Wuhan UniversityEnrolling: 1551 location