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Critical Limb Ischemia Clinical Trials

12 recruiting trials for Critical Limb Ischemia. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
12
Total Trials
12
Recruiting Now
1
Phase 3 Trials
10
Sponsors

Recruiting Trials

RECRUITINGNCT03594344

Additional Hyperbaric Oxygen After Lower Extremity Amputation

This study evaluates the effect of additional hyperbaric oxygen therapy after lower extremity amputation. The patients will be randomized after amputation to either a treatment...

Sponsor: Oslo University HospitalEnrolling: 1202 locations
RECRUITINGEarly Phase 1NCT03529019

Nutrition in Patient With Critical Limb Ischemia

A prospective pilot study examining nutritional supplements among vascular surgery patients with Critical Limb Ischemia (CLI). CLI patients have a high rate of malnutrition and...

Sponsor: Boston Medical CenterEnrolling: 301 location
RECRUITINGPhase 1NCT06359912

Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Critical Limb...

The purpose of this study is to determine if allogeneic Endothelial Progenitor Cells (EPCs) intravenous infusion to a subject with leg ulcer and/or gangrene due to poor blood flow...

Sponsor: Allife Medical Science and Technology Co., Ltd.Enrolling: 271 location
RECRUITINGNCT05971394

IBS Titan™ Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System Clinical Trial

The goal of this prospective, multicentre, single arm clinical trial is to assess the safety and effectiveness of Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System...

Sponsor: Biotyx Medical (Shenzhen) Co., Ltd.Enrolling: 1001 location
RECRUITINGPhase 4NCT05854615

Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Buerger's Disease

The goal of this observational, practice-based feasibility study is to observe the efficacy and safety of intramuscular administration of Stempeucel® in Malaysian patients with...

Sponsor: Cell Biopeutics Resources Sdn BhdEnrolling: 31 location
RECRUITINGNCT06544135

Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention

This is a preliminary prospective observational study measuring change in lower extremity temperature in response to revascularization procedure. The main question this study...

Sponsor: University Hospitals Cleveland Medical CenterEnrolling: 253 locations
RECRUITINGEarly Phase 1NCT06204237

Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects With PAOD/CLI and Healthy Volunteers...

The goal of this Phase 0 clinical trial is to evaluate safety and biodistribution of \[89Zr\]Zr-DFO-APAC in patients with peripheral arterial occlusive disease / critical limb...

Sponsor: Aplagon OyEnrolling: 101 location
RECRUITINGNCT06066268

miRNAs in Critical Limb Ischemia (miRNACLI)

For the present study, 40 patients affected by critical limb ischemia of different severity will be enrolled: patients affected by critical limb ischemia undergoing subgenual...

Sponsor: IRCCS Policlinico S. DonatoEnrolling: 801 location
RECRUITINGNCT06075940

Evaluation of the MAGNITUDE® Bioresorbable Drug-Eluting Scaffold in the Treatment of Patients With Below the Knee...

The objective of this prospective, multi-center, clinical investigation is to evaluate the MAGNITUDE BRS System for the planned treatment of narrowed infrapopliteal lesions. Up to...

Sponsor: R3 Vascular Inc.Enrolling: 301 location
RECRUITINGNCT06296576

Acceleration Time Assessment for Prediction of Critical Limb Ischemia

Critical Limb Ischaemia (CLI), the final stage of arterial disease, is a therapeutic emergency whose prognosis depends largely on the time taken to diagnose it. The growing...

Sponsor: Centre Hospitalier le MansEnrolling: 4313 locations
RECRUITINGPhase 3NCT04433572

Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee

A multicenter, randomized, double-blind, placebo-controlled trial to evaluate the effect of Temsirolimus Perivascular Injection 0.1 mg/mL on the incidence of ischemia-driven major...

Sponsor: Mercator MedSystems, Inc.Enrolling: 2502 locations
RECRUITINGPhase 2NCT06482892

TP03HN106 in Patients With Critical Limb Ischemia

Critical limb ischemia (CLI) is the most severe ischemic stage in peripheral arterial disease (PAD) of the lower limbs, characterized by decreased walking ability, resting pain...

Sponsor: Talengen Institute of Life Sciences, Shenzhen, P.R. China.Enrolling: 151 location